The Native American Rights Fund is headquartered in Boulder, Colorado, with branch offices in Washington, DC, and Anchorage, AK.

NARF is governed by a volunteer board of directors composed of thirteen Native Americans from different tribes throughout the country with a variety of expertise in Indian matters. A staff of approximately 16 attorneys handles over 50 major cases at any given time, with most of the cases taking several years to resolve. Cases are accepted on the basis of their breadth and potential importance in setting precedents and establishing important principles of Indian law.